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Claude Sonnet 4.5 vs Qwen2.5 72B Instruct
Comprehensive side-by-side LLM comparison
Claude Sonnet 4.5 leads with 34.4% higher average benchmark score. Claude Sonnet 4.5 offers 124.7K more tokens in context window than Qwen2.5 72B Instruct. Qwen2.5 72B Instruct is $17.25 cheaper per million tokens. Claude Sonnet 4.5 supports multimodal inputs. Qwen2.5 72B Instruct is available on 4 providers. Overall, Claude Sonnet 4.5 is the stronger choice for coding tasks.
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Anthropic
Claude Sonnet 4.5 was developed to bridge human thinking and machine assistance, allowing people to work with language and tools in a more conversational and natural way. Built with a focus on turning ideas into results, it represents an evolution in making AI feel less mechanical while maintaining strong capabilities across reasoning, coding, and collaborative tasks.
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Alibaba Cloud / Qwen Team
Qwen 2.5 72B was developed as the flagship text model in the Qwen 2.5 series, designed to provide advanced language capabilities with 72 billion parameters. Built to compete with frontier models in reasoning, coding, and general language tasks, it represents Qwen's most capable instruction-following model in this generation.
1 year newer
Qwen2.5 72B Instruct
Alibaba Cloud / Qwen Team
2024-09-19
Claude Sonnet 4.5
Anthropic
2025-09-29
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Pricing Comparison
Cost per million tokens (USD)
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Claude Sonnet 4.5
Input:$3.00
Output:$15.00
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Qwen2.5 72B Instruct
Input:$0.35
Output:$0.40($17.25 cheaper)
Performance Metrics
Context window and performance specifications
Average performance across 1 common benchmarks
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Claude Sonnet 4.5
Average Score:83.4%(+34.4%)
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Qwen2.5 72B Instruct
Average Score:49.0%
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Knowledge Cutoff
Training data recency comparison
Claude Sonnet 4.5
2025-01-31
More recent knowledge cutoff means awareness of newer technologies and frameworks
Provider Availability & Performance
Available providers and their performance metrics
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Claude Sonnet 4.5
2 providers
Anthropic
Throughput: 42 tok/s
Latency: 0.4ms
ZeroEval
Throughput: 42 tok/s
Latency: 0.4ms
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Claude Sonnet 4.5
Avg Score:83.4%(+34.4%)
Providers:2
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Qwen2.5 72B Instruct
Avg Score:49.0%
Providers:4