Comprehensive side-by-side LLM comparison
. Both models have their strengths depending on your specific coding needs.
OpenAI
GPT-4.5 was developed as an intermediate advancement between GPT-4 and GPT-5, designed to incorporate incremental improvements in reasoning, factuality, and instruction-following. Built to bridge generational capabilities while maintaining compatibility with existing applications, it represents a refinement of the GPT-4 architecture with enhanced performance characteristics.
MedGemma 4B was developed as a domain-specialized open-source model focused on medical and healthcare applications. Built with 4 billion parameters and training data relevant to medical contexts, it provides researchers and healthcare developers with a foundation model tailored to biomedical language understanding and generation.
2 months newer

GPT-4.5
OpenAI
2025-02-27

MedGemma 4B IT
2025-05-20
Context window and performance specifications
Available providers and their performance metrics

GPT-4.5
OpenAI

MedGemma 4B IT

GPT-4.5

MedGemma 4B IT

GPT-4.5

MedGemma 4B IT