Gemma 3 12B vs GPT-4.1 nano

Gemma 3 12B

Google DeepMind

Gemma 3 12B is a 12-billion-parameter open-weight model from Google DeepMind, released in March 2025 as part of the Gemma 3 series designed to bring multimodal reasoning to accessible hardware. The model supports both text and image inputs across a 128K token context window, extending the vision capabilities that defined the Gemma 3 generation compared to earlier text-only Gemma releases. It became widely adopted for domain-specific fine-tuning in research and enterprise settings where full multimodal capability was needed without the infrastructure demands of larger frontier models.

GPT-4.1 nano

OpenAI

GPT-4.1 nano is OpenAI's smallest member of the GPT-4.1 family, released in April 2025 alongside GPT-4.1 and GPT-4.1 mini as the latency-optimized, cost-minimized option for high-throughput applications. Positioned below GPT-4.1 mini in both size and cost, it was designed for use cases where speed and affordability dominate over raw capability — including tool calling, intent classification, short-form instruction following, and retrieval-augmented lookup tasks. Unlike its larger siblings, it supports fine-tuning, making it a practical candidate for task-specific customization at scale without incurring the cost of fine-tuning larger models.