GPT-4.1 nano vs InternS1

GPT-4.1 nano

OpenAI

GPT-4.1 nano is OpenAI's smallest member of the GPT-4.1 family, released in April 2025 alongside GPT-4.1 and GPT-4.1 mini as the latency-optimized, cost-minimized option for high-throughput applications. Positioned below GPT-4.1 mini in both size and cost, it was designed for use cases where speed and affordability dominate over raw capability — including tool calling, intent classification, short-form instruction following, and retrieval-augmented lookup tasks. Unlike its larger siblings, it supports fine-tuning, making it a practical candidate for task-specific customization at scale without incurring the cost of fine-tuning larger models.

Shanghai AI Lab

InternS1, released by Shanghai AI Laboratory at WAIC 2025 on July 26, 2025, is a multimodal scientific reasoning large language model designed for advanced problem-solving across mathematics, physics, chemistry, and related domains. It supports text, image, and potentially other scientific data formats as input, and demonstrated strong performance on competition-level scientific benchmarks. InternS1 targets open-source scientific research, STEM education, and applications requiring deep domain reasoning across natural science disciplines.