GPT-4.1 nano vs Qwen3.5-397B-A17B

GPT-4.1 nano

OpenAI

GPT-4.1 nano is OpenAI's smallest member of the GPT-4.1 family, released in April 2025 alongside GPT-4.1 and GPT-4.1 mini as the latency-optimized, cost-minimized option for high-throughput applications. Positioned below GPT-4.1 mini in both size and cost, it was designed for use cases where speed and affordability dominate over raw capability — including tool calling, intent classification, short-form instruction following, and retrieval-augmented lookup tasks. Unlike its larger siblings, it supports fine-tuning, making it a practical candidate for task-specific customization at scale without incurring the cost of fine-tuning larger models.

Alibaba / Qwen

Qwen3.5-397B-A17B is a 397-billion-parameter mixture-of-experts model from Alibaba's Qwen team, released in February 2026 as the open-weight flagship of the Qwen3.5 series, featuring 17 billion active parameters per forward pass through a hybrid linear-attention and sparse-MoE architecture based on Gated Delta Networks. The model was co-trained on text, images, and video using early fusion, making it natively multimodal across a 262K token context window, while achieving significantly higher inference throughput than comparable dense models due to its sparse computation design. At release it was one of the most capable open-weight models publicly available, offered under Apache 2.0 and accessible through Alibaba's DashScope API as the Qwen3.5-Plus endpoint.