Llama-3.1 Nemotron Ultra 253B vs Qwen2 72B Instruct

Llama-3.1 Nemotron Ultra 253B

NVIDIA

Llama-3.1-Nemotron-Ultra-253B-v1 is a 253-billion-parameter model from NVIDIA, derived from Meta's Llama 3.1 405B using neural architecture search (NAS) compression combined with NVIDIA's Nemotron post-training pipeline, which recovers and exceeds the base model's capability after structural compression. Released in April 2025, it supports toggling between a standard instruction mode and an extended reasoning mode via system prompt, allowing the same model to handle both rapid responses and deliberate chain-of-thought tasks. It is the flagship of the Nemotron family, available open-weight on HuggingFace and through NVIDIA NIM for enterprise inference.

Alibaba / Qwen

Qwen2-72B-Instruct is a 72-billion-parameter language model released by Alibaba's Qwen team in June 2024, serving as the flagship of the Qwen2 generation and representing a major step in open-weight multilingual modeling. Trained on data spanning 30+ languages with strong coverage of code and structured reasoning, the model was among the first openly released 70B-class models to demonstrate competitive performance across diverse benchmarks. It established the foundation architecture and training methodology that the Qwen2.5 series would later extend.