Phi-3.5-MoE Instruct vs Qwen2.5 72B Instruct

Phi-3.5-MoE Instruct

Microsoft

Phi-3.5-MoE-instruct is a sparse mixture-of-experts model from Microsoft's Phi research team, released in August 2024 with 42 billion total parameters across 16 experts and approximately 6.6 billion active parameters per forward pass. The model applies Microsoft's small-data, high-quality training philosophy — developed across earlier Phi generations — to a MoE architecture, targeting reasoning quality comparable to much larger dense models at a fraction of the inference compute. Released under the MIT license, it was notable in the research community for demonstrating that MoE efficiency gains could be realized at smaller total parameter counts than typical large-scale MoE deployments.

Alibaba / Qwen

Qwen2.5-72B-Instruct is the flagship of Alibaba's Qwen2.5 series, a 72-billion-parameter open-weight model released in September 2024 after training on 18 trillion tokens spanning code, mathematics, and multilingual text. It offers strong generalist performance across coding, instruction-following, and structured reasoning while remaining fully open-weight under Apache 2.0 — a combination that made it a widely referenced model in open-source evaluations and community benchmarking. The 128K context window and built-in structured output support made it a common choice for document analysis and multi-step agentic pipeline development.