Qwen2.5 72B Instruct vs UI-TARS-72B-DPO

Alibaba / Qwen

Qwen2.5-72B-Instruct is the flagship of Alibaba's Qwen2.5 series, a 72-billion-parameter open-weight model released in September 2024 after training on 18 trillion tokens spanning code, mathematics, and multilingual text. It offers strong generalist performance across coding, instruction-following, and structured reasoning while remaining fully open-weight under Apache 2.0 — a combination that made it a widely referenced model in open-source evaluations and community benchmarking. The 128K context window and built-in structured output support made it a common choice for document analysis and multi-step agentic pipeline development.

ByteDance

UI-TARS-72B-DPO, released by ByteDance in early 2025, is a 72 billion parameter multimodal large language model from the UI-TARS family, built on Qwen-2-VL and fine-tuned for automated GUI interaction and computer control. It features native understanding of screenshots, UI elements, and web interfaces, achieving strong results across GUI benchmarks for perception, grounding, and agentic control. UI-TARS-72B-DPO targets computer-use agents, web automation, and applications requiring robust visual UI reasoning.